Endotoxins yog cov kab mob me me uas tau txais los ntawm hydrophobic lipopolysaccharides (LPS) molecules nyob rau hauv lub cell sab nrauv ntawm cov kab mob gram-negative.Endotoxins muaj cov tub ntxhais polysaccharide saw, O-specific polysaccharide side chains (O-antigen) thiab lipid compenent, Lipid A, uas yog lub luag haujlwm rau cov tshuaj lom.Cov kab mob tso cov endotoxin ntau ntau thaum lub cell tuag thiab thaum lawv nquag loj hlob thiab faib.Ib qho Escherichia coli muaj txog 2 lab LPS molecules ib lub cell.
Endotoxin tuaj yeem kis tau yooj yim labwares, thiab nws lub xub ntiag tuaj yeem cuam tshuam ob qho tib si hauv vitro thiab hauv vivo kev sim.Thiab rau cov khoom lag luam parenteral, cov khoom lag luam parenteral kis nrog endotoxins suav nrog LPS tuaj yeem ua rau kev txhim kho kub taub hau, ua rau muaj kev mob tshwm sim, poob siab, lub cev tsis ua haujlwm thiab kev tuag ntawm tib neeg.Rau cov khoom siv lim ntshav, LPS tuaj yeem hloov pauv los ntawm daim nyias nyias nrog qhov pore loj los ntawm rov qab pom los ntawm cov kua dej lim ntshav mus rau cov ntshav, cov teeb meem inflammatory yuav tshwm sim raws li.
Endotoxin kuaj pom los ntawm Lyophilized Amebocyte Lysate (TAL).Bioendo tau mob siab rau kev tshawb fawb, tsim thiab tsim TAL reagent rau ntau tshaj plaub xyoo lawm.Peb cov khoom lag luam npog tag nrho cov txheej txheem ua haujlwm los kuaj cov tshuaj endotoxin, uas yog cov txheej txheem gel-clot, cov txheej txheem turbidimetric, thiab cov txheej txheem chromogenic.
Post lub sij hawm: Jan-29-2019
